Recently had Amitriptyline added as a second antidepressant. I'm on a small dose at night and it knocks me right out about 2 hours after I take it. Works better than any sleeping pills I've ever taken. But that's about all it has going for it. It's not really doing anything for my depression and it makes me groggy during the day. Also I have pretty bad dry mouth. It does have a calming effect during the day which I like, but I don't know if it's worth it since it leaves me so groggy.